Accurately simulating systems governed by PDEs, such as voltage fields in cardiac electrophysiology (EP) modelling, remains a significant modelling challenge. Traditional numerical solvers are computationally expensive and sensitive to discretisation, while canonical deep learning methods are data-hungry and struggle with chaotic dynamics and long-term predictions. Physics-Informed Neural Networks (PINNs) mitigate some of these issues by incorporating physical constraints in the learning process, yet they remain limited by mesh resolution and long-term predictive stability. In this work, we propose a Physics-Informed Neural Operator (PINO) approach to solve PDE problems in cardiac EP. Unlike PINNs, PINO models learn mappings between function spaces, allowing them to generalise to multiple mesh resolutions and initial conditions. Our results show that PINO models can accurately reproduce cardiac EP dynamics over extended time horizons and across multiple propagation scenarios, including zero-shot evaluations on scenarios unseen during training. Additionally, our PINO models maintain high predictive quality in long roll-outs (where predictions are recursively fed back as inputs), and can scale their predictive resolution by up to 10x the training resolution. These advantages come with a significant reduction in simulation time compared to numerical PDE solvers, highlighting the potential of PINO-based approaches for efficient and scalable cardiac EP simulations.

Accurately quantifying long-term risk probabilities in diverse stochastic systems is essential for safety-critical control. However, existing sampling-based and partial differential equation (PDE)-based methods often struggle to handle complex varying dynamics. Physics-informed neural networks learn surrogate mappings for risk probabilities from varying system parameters of fixed and finite dimensions, yet can not account for functional variations in system dynamics. To address these challenges, we introduce physics-informed neural operator (PINO) methods to risk quantification problems, to learn mappings from varying \textit{functional} system dynamics to corresponding risk probabilities. Specifically, we propose Neural Spline Operators (NeSO), a PINO framework that leverages B-spline representations to improve training efficiency and achieve better initial and boundary condition enforcements, which are crucial for accurate risk quantification. We provide theoretical analysis demonstrating the universal approximation capability of NeSO. We also present two case studies, one with varying functional dynamics and another with high-dimensional multi-agent dynamics, to demonstrate the efficacy of NeSO and its significant online speed-up over existing methods. The proposed framework and the accompanying universal approximation theorem are expected to be beneficial for other control or PDE-related problems beyond risk quantification.

Accurate real-time prediction of phase-resolved ocean wave fields remains a critical yet largely unsolved problem, primarily due to the absence of practical data assimilation methods for reconstructing initial conditions from sparse or indirect wave measurements. While recent advances in supervised deep learning have shown potential for this purpose, they require large labelled datasets of ground truth wave data, which are infeasible to obtain in real-world scenarios. To overcome this limitation, we propose a Physics-Informed Neural Operator (PINO) framework for reconstructing spatially and temporally phase-resolved, nonlinear ocean wave fields from sparse measurements, without the need for ground truth data during training. This is achieved by embedding residuals of the free surface boundary conditions of ocean gravity waves into the loss function of the PINO, constraining the solution space in a soft manner. After training, we validate our approach using highly realistic synthetic wave data and demonstrate the accurate reconstruction of nonlinear wave fields from both buoy time series and radar snapshots. Our results indicate that PINOs enable accurate, real-time reconstruction and generalize robustly across a wide range of wave conditions, thereby paving the way for operational, data-driven wave reconstruction and prediction in realistic marine environments.

Physics-informed neural operators (PINOs) have emerged as powerful tools for learning solution operators of partial differential equations (PDEs). Recent research has demonstrated that incorporating Lie point symmetry information can significantly enhance the training efficiency of PINOs, primarily through techniques like data, architecture, and loss augmentation. In this work, we focus on the latter, highlighting that point symmetries oftentimes result in no training signal, limiting their effectiveness in many problems. To address this, we propose a novel loss augmentation strategy that leverages evolutionary representatives of point symmetries, a specific class of generalized symmetries of the underlying PDE. These generalized symmetries provide a richer set of generators compared to standard symmetries, leading to a more informative training signal. We demonstrate that leveraging evolutionary representatives enhances the performance of neural operators, resulting in improved data efficiency and accuracy during training.

The physics-informed neural operator (PINO) is a machine learning architecture that has shown promising empirical results for learning partial differential equations. PINO uses the Fourier neural operator (FNO) architecture to overcome the optimization challenges often faced by physics-informed neural networks. Since the convolution operator in PINO uses the Fourier series representation, its gradient can be computed exactly on the Fourier space. While Fourier series cannot represent nonperiodic functions, PINO and FNO still have the expressivity to learn nonperiodic problems with Fourier extension via padding. However, computing the Fourier extension in the physics-informed optimization requires solving an ill-conditioned system, resulting in inaccurate derivatives which prevent effective optimization. In this work, we present an architecture that leverages Fourier continuation (FC) to apply the exact gradient method to PINO for nonperiodic problems. This paper investigates three different ways that FC can be incorporated into PINO by testing their performance on a 1D blowup problem. Experiments show that FC-PINO outperforms padded PINO, improving equation loss by several orders of magnitude, and it can accurately capture the third order derivatives of nonsmooth solution functions.

Machine learning methods have recently shown promise in solving partial differential equations (PDEs). They can be classified into two broad categories: approximating the solution function and learning the solution operator. The Physics-Informed Neural Network (PINN) is an example of the former while the Fourier neural operator (FNO) is an example of the latter. Both these approaches have shortcomings. The optimization in PINN is challenging and prone to failure, especially on multi-scale dynamic systems.